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ABCG2 downregulation in glioma stem cells enhances the therapeutic efficacy of demethoxycurcumin

We analyzed the role of ABCG2, a drug transporter, in determining the sensitivity of glioma stem cells (GSCs) to demethoxycurcumin (DMC). We first demonstrated that ABCG2 is more highly expressed in GSCs than primary astrocytes. Modulation of ABCG2 levels in GSCs by transfection of ABCG2 shRNA or a...

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Detalles Bibliográficos
Autores principales:	Chen, Long, Shi, Lei, Wang, Wenhua, Zhou, Youxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522142/ https://www.ncbi.nlm.nih.gov/pubmed/28591733 http://dx.doi.org/10.18632/oncotarget.18018

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