Glibenclamide, a diabetic drug, prevents acute radiation-induced liver injury of mice via up-regulating intracellular ROS and subsequently activating Akt–NF-κB pathway

BACKGROUND: Acute radiation-induced liver injury is a limitation for hepatoma radiotherapy. Come so far the clinical treatments are insufficient. The effective, specific, low toxicity and novel drugs are in powerful need. Glibenclamide is a common hypoglycemic. Some studies have revealed its relatio...

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Detalles Bibliográficos
Autores principales: Liu, Hu, Wang, Shichao, Wu, Zhao, Huang, Ziyun, Chen, Wei you, Yang, Yanyong, Cui, Jianguo, Liu, Cong, Zhao, Hainan, Guo, Jiaming, Zhang, Pei, Gao, Fu, Li, Bailong, Cai, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522206/
https://www.ncbi.nlm.nih.gov/pubmed/28380448
http://dx.doi.org/10.18632/oncotarget.16501

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