Cargando…

PDCD1 (PD-1) promoter methylation predicts outcome in head and neck squamous cell carcinoma patients

BACKGROUND: Biomarkers that facilitate the prediction of disease recurrence in head and neck squamous cell carcinoma (HNSCC) may enable physicians to personalize treatment. In the current study, DNA promoter methylation of programmed cell death 1 (PDCD1, PD-1) was evaluated as a prognostic biomarker...

Descripción completa

Detalles Bibliográficos
Autores principales:	Goltz, Diane, Gevensleben, Heidrun, Dietrich, Joern, Schroeck, Friederike, de Vos, Luka, Droege, Freya, Kristiansen, Glen, Schroeck, Andreas, Landsberg, Jennifer, Bootz, Friedrich, Dietrich, Dimo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522222/ https://www.ncbi.nlm.nih.gov/pubmed/28487502 http://dx.doi.org/10.18632/oncotarget.17354

Ejemplares similares

PD-1 (PDCD1) Promoter Methylation Is a Prognostic Factor in Patients With Diffuse Lower-Grade Gliomas Harboring Isocitrate Dehydrogenase (IDH) Mutations
por: Röver, Lea Kristin, et al.
Publicado: (2018)

Clinical performance validation of PITX2 DNA methylation as prognostic biomarker in patients with head and neck squamous cell carcinoma
por: Sailer, Verena, et al.
Publicado: (2017)

PITX2 and PANCR DNA methylation predicts overall survival in patients with head and neck squamous cell carcinoma
por: Sailer, Verena, et al.
Publicado: (2016)

PITX3 DNA methylation is an independent predictor of overall survival in patients with head and neck squamous cell carcinoma
por: Sailer, Verena, et al.
Publicado: (2017)

Comparison of quantification algorithms for circulating cell-free DNA methylation biomarkers in blood plasma from cancer patients
por: de Vos, Luka, et al.
Publicado: (2017)

PD-L1 (CD274) and PD-L2 (PDCD1LG2) promoter methylation is associated with HPV infection and transcriptional repression in head and neck squamous cell carcinomas
por: Franzen, Alina, et al.
Publicado: (2017)

PD-L1 promoter methylation is a prognostic biomarker for biochemical recurrence-free survival in prostate cancer patients following radical prostatectomy
por: Gevensleben, Heidrun, et al.
Publicado: (2016)

Intragenic DNA methylation of PITX1 and the adjacent long non-coding RNA C5orf66-AS1 are prognostic biomarkers in patients with head and neck squamous cell carcinomas
por: Sailer, Verena, et al.
Publicado: (2018)

CXCL12 promoter methylation and PD-L1 expression as prognostic biomarkers in prostate cancer patients
por: Goltz, Diane, et al.
Publicado: (2016)

Potential of quantitative SEPT9 and SHOX2 methylation in plasmatic circulating cell-free DNA as auxiliary staging parameter in colorectal cancer: a prospective observational cohort study
por: Bergheim, Julia, et al.
Publicado: (2018)

PD-L1: a novel prognostic biomarker in head and neck squamous cell carcinoma
por: Müller, Tim, et al.
Publicado: (2017)

Molecular and immune correlates of TIM-3 (HAVCR2) and galectin 9 (LGALS9) mRNA expression and DNA methylation in melanoma
por: Holderried, Tobias A. W., et al.
Publicado: (2019)

Diagnostic and prognostic value of SHOX2 and SEPT9 DNA methylation and cytology in benign, paramalignant, and malignant ascites
por: Jung, Maria, et al.
Publicado: (2016)

DNA methylation of indoleamine 2,3-dioxygenase 1 (IDO1) in head and neck squamous cell carcinomas correlates with IDO1 expression, HPV status, patients’ survival, immune cell infiltrates, mutational load, and interferon γ signature
por: Sailer, Verena, et al.
Publicado: (2019)

2nd International Wigner Symposium
por: Doebner, Heinz Dietrich, et al.
Publicado: (1993)

CTLA4 promoter methylation predicts response and progression-free survival in stage IV melanoma treated with anti-CTLA-4 immunotherapy (ipilimumab)
por: Fietz, Simon, et al.
Publicado: (2020)

CTLA4 DNA methylation is associated with CTLA-4 expression and predicts response to immunotherapy in head and neck squamous cell carcinoma
por: Hoffmann, Friederike, et al.
Publicado: (2023)

Comprehensive analysis of tumor necrosis factor receptor TNFRSF9 (4-1BB) DNA methylation with regard to molecular and clinicopathological features, immune infiltrates, and response prediction to immunotherapy in melanoma
por: Fröhlich, Anne, et al.
Publicado: (2020)

PITX3 promoter methylation is a prognostic biomarker for biochemical recurrence-free survival in prostate cancer patients after radical prostatectomy
por: Holmes, Emily Eva, et al.
Publicado: (2016)

DNA Methylation of PITX2 and PANCR Is Prognostic for Overall Survival in Patients with Resected Adenocarcinomas of the Biliary Tract
por: Uhl, Barbara, et al.
Publicado: (2016)

DNA methylation regulates TIGIT expression within the melanoma microenvironment, is prognostic for overall survival, and predicts progression-free survival in patients treated with anti-PD-1 immunotherapy
por: Niebel, Dennis, et al.
Publicado: (2022)

Quantum mechanics on phase space
por: Schroeck, Franklin E
Publicado: (1996)

Prognostic and predictive value of PD-L2 DNA methylation and mRNA expression in melanoma
por: Hoffmann, Friederike, et al.
Publicado: (2020)

Nectin-4 is widely expressed in head and neck squamous cell carcinoma
por: Sanders, Christine, et al.
Publicado: (2022)

ICOS DNA methylation regulates melanoma cell-intrinsic ICOS expression, is associated with melanoma differentiation, prognosis, and predicts response to immune checkpoint blockade
por: Ralser, Damian J., et al.
Publicado: (2023)

Molecular, clinicopathological, and immune correlates of LAG3 promoter DNA methylation in melanoma
por: Fröhlich, Anne, et al.
Publicado: (2020)

SEPT9 and SHOX2 DNA methylation status and its utility in the diagnosis of colonic adenomas and colorectal adenocarcinomas
por: Semaan, Alexander, et al.
Publicado: (2016)

Pneumoscrotum With Extensive Penile and Abdominal Subcutaneous Emphysema: A Case Report of Uncertain Etiology
por: Raffin, Eric, et al.
Publicado: (2017)

Fibroblast growth factor (FGF), FGF receptor (FGFR), and cyclin D1 (CCND1) DNA methylation in head and neck squamous cell carcinomas is associated with transcriptional activity, gene amplification, human papillomavirus (HPV) status, and sensitivity to tyrosine kinase inhibitors
por: Bao, Yilin, et al.
Publicado: (2021)

Upregulated PD-1 Expression Is Associated with the Development of Systemic Lupus Erythematosus, but Not the PD-1.1 Allele of the PDCD1 Gene
por: Jiao, Qingqing, et al.
Publicado: (2014)

Late versus non-late presentation of HIV/AIDS: an economic impact analysis
por: Grabmeier-Pfistershammer, K, et al.
Publicado: (2010)

Relationship of PD-1 (PDCD1) and PD-L1 (CD274) Single Nucleotide Polymorphisms with Polycystic Ovary Syndrome
por: Han, Rui, et al.
Publicado: (2021)

PDCD1 Polymorphisms May Predict Response to Anti-PD-1 Blockade in Patients With Metastatic Melanoma
por: Parakh, Sagun, et al.
Publicado: (2021)

H3K27me3 and EZH2 expression in melanoma: relevance for melanoma progression and response to immune checkpoint blockade
por: Hoffmann, Friederike, et al.
Publicado: (2020)

Securing Smart Grid Enabled Home Area Networks with Retro-Reflective Visible Light Communication
por: Salas, Mathew, et al.
Publicado: (2023)

Epigenetic modification of the PD-1 (Pdcd1) promoter in effector CD4(+) T cells tolerized by peptide immunotherapy
por: McPherson, Rhoanne C, et al.
Publicado: (2014)

Identification of PDCD1 and PDCD1LG2 as Prognostic Biomarkers and Associated with Immune Infiltration in Hepatocellular Carcinoma
por: Li, Wang, et al.
Publicado: (2022)

Hyperprogressive Disease during Anti-PD-1 (PDCD1) / PD-L1 (CD274) Therapy: A Systematic Review and Meta-Analysis
por: Kim, Jong Yeob, et al.
Publicado: (2019)

Improved PCR Performance Using Template DNA from Formalin-Fixed and Paraffin-Embedded Tissues by Overcoming PCR Inhibition
por: Dietrich, Dimo, et al.
Publicado: (2013)

Time Trends and Predictors of Abnormal Postoperative Body Temperature in Infants Transported to the Intensive Care Unit
por: Schroeck, Hedwig, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_cc8r4p1c8l6qtdl54v99tbbmu5