Recombinant SjP40 protein enhances p27 promoter expression in hepatic stellate cells via an E2F1-dependent mechanism

The p27 protein plays a critical role in cell cycle arrest. Our previous studies have demonstrated that recombinant P40 protein from Schistosoma japonicum (rSjP40) could induce G1 phase arrest of cell cycle. We, therefore, attempted to observe the effect of rSjP40 on p27 promoter activity in LX-2 ce...

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Detalles Bibliográficos
Autores principales: Duan, Yinong, Lyu, Lei, Zhu, Dandan, Wang, Jianxin, Chen, Jinling, Chen, Liuting, Yang, Chunzhao, Sun, Xiaolei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522240/
https://www.ncbi.nlm.nih.gov/pubmed/28489573
http://dx.doi.org/10.18632/oncotarget.17248

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