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Locally-applied 5-fluorouracil-loaded slow-release patch prevents pancreatic cancer growth in an orthotopic mouse model

To obtain improved efficacy against pancreatic cancer, we investigated the efficacy and safety of a locally-applied 5-fluorouracil (5-FU)-loaded polymeric patch on pancreatic tumors in an orthotopic nude-mouse model. The 5-FU-releasing polymeric patch was produced by 3D printing. After application o...

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Detalles Bibliográficos
Autores principales: Shim, In Kyong, Yi, Hye-Jin, Yi, Hee-Gyeong, Lee, Chan Mi, Lee, Yu Na, Choi, Yeong-Jin, Jeong, Seong-Yun, Jun, Eunsung, Hoffman, Robert M., Cho, Dong-Woo, Kim, Song Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522260/
https://www.ncbi.nlm.nih.gov/pubmed/28498800
http://dx.doi.org/10.18632/oncotarget.17370