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Baicalein decreases uric acid and prevents hyperuricemic nephropathy in mice
Baicalein, a natural flavonoid, is structurally advantageous for binding to xanthine oxidoreductase. In our study, molecular docking analysis and Surface Plasmon Resonance revealed a direct interaction between baicalein and xanthine oxidoreductase. Moreover, 50 mg/kg/d baicalein treatment significan...
Autores principales: | Meng, Xiaolu, Mao, Zhuo, Li, Xin, Zhong, Dandan, Li, Min, Jia, Yingli, Wei, Jing, Yang, Baoxue, Zhou, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522264/ https://www.ncbi.nlm.nih.gov/pubmed/28445133 http://dx.doi.org/10.18632/oncotarget.16928 |
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