Role of Delta-like 4 in Jagged1-induced tumour angiogenesis and tumour growth

Delta-like 4 (DLL4) and Jagged1 (JAG1) are two key Notch ligands implicated in tumour angiogenesis. They were shown to have opposite effects on mouse retinal and adult regenerative angiogenesis. In tumours, both ligands are upregulated but their relative effects and interactions in tumour biology, p...

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Detalles Bibliográficos
Autores principales: Oon, Chern Ein, Bridges, Esther, Sheldon, Helen, Sainson, Richard C.A., Jubb, Adrian, Turley, Helen, Leek, Russell, Buffa, Francesca, Harris, Adrian L., Li, Ji-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522274/
https://www.ncbi.nlm.nih.gov/pubmed/28445154
http://dx.doi.org/10.18632/oncotarget.16969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522274/
https://www.ncbi.nlm.nih.gov/pubmed/28445154
http://dx.doi.org/10.18632/oncotarget.16969

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