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SET mediates TCE-induced liver cell apoptosis through dephosphorylation and upregulation of nucleolin

Trichloroethylene (TCE) is an occupational and environmental chemical that can cause severe hepatotoxicity. While our previous studies showed that the phosphatase inhibitor SET is a key mediator of TCE-induced liver cell apoptosis, the molecular mechanisms remain elusive. Using quantitative phosphop...

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Detalles Bibliográficos
Autores principales: Ren, Xiaohu, Huang, Xinfeng, Yang, Xifei, Liu, Yungang, Liu, Wei, Huang, Haiyan, Wu, Desheng, Zou, Fei, Liu, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522280/
https://www.ncbi.nlm.nih.gov/pubmed/28402964
http://dx.doi.org/10.18632/oncotarget.16785