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NatB-mediated protein N-α-terminal acetylation is a potential therapeutic target in hepatocellular carcinoma
The identification of new targets for systemic therapy of hepatocellular carcinoma (HCC) is an urgent medical need. Recently, we showed that hNatB catalyzes the N-α-terminal acetylation of 15% of the human proteome and that this action is necessary for proper actin cytoskeleton structure and functio...
Autores principales: | Neri, Leire, Lasa, Marta, Elosegui-Artola, Alberto, D'Avola, Delia, Carte, Beatriz, Gazquez, Cristina, Alve, Sara, Roca-Cusachs, Pere, Iñarrairaegui, Mercedes, Herrero, Jose, Prieto, Jesús, Sangro, Bruno, Aldabe, Rafael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522283/ https://www.ncbi.nlm.nih.gov/pubmed/28498797 http://dx.doi.org/10.18632/oncotarget.17332 |
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