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Non-homologous end joining induced alterations in DNA methylation: A source of permanent epigenetic change

In addition to genetic mutations, epigenetic revision plays a major role in the development and progression of cancer; specifically, inappropriate DNA methylation or demethylation of CpG residues may alter the expression of genes that promote tumorigenesis. We hypothesize that DNA repair, specifical...

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Detalles Bibliográficos
Autores principales: Allen, Brittany, Pezone, Antonio, Porcellini, Antonio, Muller, Mark T., Masternak, Michal M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522286/
https://www.ncbi.nlm.nih.gov/pubmed/28423717
http://dx.doi.org/10.18632/oncotarget.16122

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