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Non-homologous end joining induced alterations in DNA methylation: A source of permanent epigenetic change
In addition to genetic mutations, epigenetic revision plays a major role in the development and progression of cancer; specifically, inappropriate DNA methylation or demethylation of CpG residues may alter the expression of genes that promote tumorigenesis. We hypothesize that DNA repair, specifical...
Autores principales: | Allen, Brittany, Pezone, Antonio, Porcellini, Antonio, Muller, Mark T., Masternak, Michal M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522286/ https://www.ncbi.nlm.nih.gov/pubmed/28423717 http://dx.doi.org/10.18632/oncotarget.16122 |
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