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Efficacy of an HSP90 inhibitor, ganetespib, in preclinical thyroid cancer models

Heat shock protein 90 is a molecular chaperon that maintains the correct folding and function of multiple client proteins. The inhibition of heat shock protein 90, which leads to the simultaneous degradation of multiple proteins involved in oncogenic signaling pathways, has revealed an innovative st...

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Detalles Bibliográficos
Autores principales:	Lin, Shu-Fu, Lin, Jen-Der, Hsueh, Chuen, Chou, Ting-Chao, Yeh, Chun-Nan, Chen, Ming-Huang, Wong, Richard J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522292/ https://www.ncbi.nlm.nih.gov/pubmed/28476040 http://dx.doi.org/10.18632/oncotarget.17180

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