Activation of Akt characterizes estrogen receptor positive human breast cancers which respond to anthracyclines

Anthracyclines are key components of human breast cancer chemotherapy. Here, we explored the role of Akt signaling in anthracycline resistance. The antitumor activity of doxorubicin and Akt inhibitor A-443654 alone or combined was examined in estrogen receptor (ER) positive and negative human breast...

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Detalles Bibliográficos
Autores principales: Yndestad, Synnøve, Austreid, Eilin, Svanberg, Ida R., Knappskog, Stian, Lønning, Per E., Eikesdal, Hans P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522318/
https://www.ncbi.nlm.nih.gov/pubmed/28476032
http://dx.doi.org/10.18632/oncotarget.17167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522318/
https://www.ncbi.nlm.nih.gov/pubmed/28476032
http://dx.doi.org/10.18632/oncotarget.17167

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