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New tumor suppressor microRNAs target glypican-3 in human liver cancer

Glypican-3 (GPC3) is an oncogene, frequently upregulated in liver malignancies such as hepatocellular carcinoma (HCC) and hepatoblastoma and constitutes a potential molecular target for therapy in liver cancer. Using a functional screening system, we identified 10 new microRNAs controlling GPC3 expr...

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Detalles Bibliográficos
Autores principales: Cartier, Flora, Indersie, Emilie, Lesjean, Sarah, Charpentier, Justine, Hooks, Katarzyna B., Ghousein, Amani, Desplat, Angélique, Dugot-Senant, Nathalie, Trézéguet, Véronique, Sagliocco, Francis, Hagedorn, Martin, Grosset, Christophe F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522324/
https://www.ncbi.nlm.nih.gov/pubmed/28476031
http://dx.doi.org/10.18632/oncotarget.17162

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