Anti-proliferative and anti-secretory effects of everolimus on human pancreatic neuroendocrine tumors primary cultures: is there any benefit from combination with somatostatin analogs?

Therapeutic management of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) is challenging. The mammalian target of rapamycin (mTOR) inhibitor everolimus recently obtained approval from the Food and Drug Administration for the treatment of patients with advanced pancreatic neuroendocrine tumor...

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Detalles Bibliográficos
Autores principales: Mohamed, Amira, Romano, David, Saveanu, Alexandru, Roche, Catherine, Albertelli, Manuela, Barbieri, Federica, Brue, Thierry, Niccoli, Patricia, Delpero, Jean-Robert, Garcia, Stephane, Ferone, Diego, Florio, Tullio, Moutardier, Vincent, Poizat, Flora, Barlier, Anne, Gerard, Corinne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522327/
https://www.ncbi.nlm.nih.gov/pubmed/28454119
http://dx.doi.org/10.18632/oncotarget.17008

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