Two-Stage Urethroplasty with Buccal Mucosa for Penoscrotal Hypospadias Reconstruction in a Male with a 46,XX Karyotype

We present a case regarding a 32-year old African male with penoscrotal hypospadias, left cryptorchidism and a left inguinal hernia. There were moderate masculinization characteristics. He underwent a Lichtenstein hernia repair with perioperative biopsies of the left inguinal testis and epididymis....

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Autores principales: D'hulst, Pieter, Darras, Jochen, Joniau, Steven, Mattelaer, Pieter, Winne, Linsey, Ponette, Diederik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Trauma and Reconstruction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522374/
https://www.ncbi.nlm.nih.gov/pubmed/28752067
http://dx.doi.org/10.1016/j.eucr.2017.06.016
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author D'hulst, Pieter
Darras, Jochen
Joniau, Steven
Mattelaer, Pieter
Winne, Linsey
Ponette, Diederik
author_facet D'hulst, Pieter
Darras, Jochen
Joniau, Steven
Mattelaer, Pieter
Winne, Linsey
Ponette, Diederik
author_sort D'hulst, Pieter
collection PubMed
description We present a case regarding a 32-year old African male with penoscrotal hypospadias, left cryptorchidism and a left inguinal hernia. There were moderate masculinization characteristics. He underwent a Lichtenstein hernia repair with perioperative biopsies of the left inguinal testis and epididymis. Microscopic examination showed a Sertoli-only left testis with Leydig-cell hyperplasia and the left epididymis consisted of ovarian tissue with corpora albicantia and maturing follicles. Endocrinological evaluation showed a sex-determining region Y (SRY) negative 46,XX karyotype. We successfully performed a two-stage urethroplasty with buccal mucosa graft to reconstruct his penoscrotal hypospadias.
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spelling pubmed-55223742017-07-27 Two-Stage Urethroplasty with Buccal Mucosa for Penoscrotal Hypospadias Reconstruction in a Male with a 46,XX Karyotype D'hulst, Pieter Darras, Jochen Joniau, Steven Mattelaer, Pieter Winne, Linsey Ponette, Diederik Urol Case Rep Trauma and Reconstruction We present a case regarding a 32-year old African male with penoscrotal hypospadias, left cryptorchidism and a left inguinal hernia. There were moderate masculinization characteristics. He underwent a Lichtenstein hernia repair with perioperative biopsies of the left inguinal testis and epididymis. Microscopic examination showed a Sertoli-only left testis with Leydig-cell hyperplasia and the left epididymis consisted of ovarian tissue with corpora albicantia and maturing follicles. Endocrinological evaluation showed a sex-determining region Y (SRY) negative 46,XX karyotype. We successfully performed a two-stage urethroplasty with buccal mucosa graft to reconstruct his penoscrotal hypospadias. Elsevier 2017-07-18 /pmc/articles/PMC5522374/ /pubmed/28752067 http://dx.doi.org/10.1016/j.eucr.2017.06.016 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Trauma and Reconstruction
D'hulst, Pieter
Darras, Jochen
Joniau, Steven
Mattelaer, Pieter
Winne, Linsey
Ponette, Diederik
Two-Stage Urethroplasty with Buccal Mucosa for Penoscrotal Hypospadias Reconstruction in a Male with a 46,XX Karyotype
title Two-Stage Urethroplasty with Buccal Mucosa for Penoscrotal Hypospadias Reconstruction in a Male with a 46,XX Karyotype
title_full Two-Stage Urethroplasty with Buccal Mucosa for Penoscrotal Hypospadias Reconstruction in a Male with a 46,XX Karyotype
title_fullStr Two-Stage Urethroplasty with Buccal Mucosa for Penoscrotal Hypospadias Reconstruction in a Male with a 46,XX Karyotype
title_full_unstemmed Two-Stage Urethroplasty with Buccal Mucosa for Penoscrotal Hypospadias Reconstruction in a Male with a 46,XX Karyotype
title_short Two-Stage Urethroplasty with Buccal Mucosa for Penoscrotal Hypospadias Reconstruction in a Male with a 46,XX Karyotype
title_sort two-stage urethroplasty with buccal mucosa for penoscrotal hypospadias reconstruction in a male with a 46,xx karyotype
topic Trauma and Reconstruction
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522374/
https://www.ncbi.nlm.nih.gov/pubmed/28752067
http://dx.doi.org/10.1016/j.eucr.2017.06.016
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