Cargando…

Distinct selective forces and Neanderthal introgression shaped genetic diversity at genes involved in neurodevelopmental disorders

In addition to high intelligence, humans evolved specialized social-cognitive skills, which are specifically affected in children with autism spectrum disorder (ASD). Genes affected in ASD represent suitable candidates to study the evolution of human social cognition. We performed an evolutionary an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mozzi, Alessandra, Forni, Diego, Cagliani, Rachele, Pozzoli, Uberto, Clerici, Mario, Sironi, Manuela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522412/ https://www.ncbi.nlm.nih.gov/pubmed/28733602 http://dx.doi.org/10.1038/s41598-017-06440-4

Ejemplares similares

Intrinsically disordered regions are abundant in simplexvirus proteomes and display signatures of positive selection
por: Mozzi, Alessandra, et al.
Publicado: (2020)

The Diversity of Mammalian Hemoproteins and Microbial Heme Scavengers Is Shaped by an Arms Race for Iron Piracy
por: Mozzi, Alessandra, et al.
Publicado: (2018)

Antigenic variation of SARS‐CoV‐2 in response to immune pressure
por: Forni, Diego, et al.
Publicado: (2020)

OASes and STING: Adaptive Evolution in Concert
por: Mozzi, Alessandra, et al.
Publicado: (2015)

Dating the Emergence of Human Endemic Coronaviruses
por: Forni, Diego, et al.
Publicado: (2022)

Evolutionary analysis of exogenous and integrated HHV-6A/HHV-6B populations
por: Forni, Diego, et al.
Publicado: (2020)

A complex evolutionary relationship between HHV-6A and HHV-6B
por: Forni, Diego, et al.
Publicado: (2019)

Retraction to: A complex evolutionary relationship between HHV-6A and HHV-6B
por: Forni, Diego, et al.
Publicado: (2019)

Albuminoid Genes: Evolving at the Interface of Dispensability and Selection
por: Mozzi, Alessandra, et al.
Publicado: (2014)

Adaptation of the endemic coronaviruses HCoV-OC43 and HCoV-229E to the human host
por: Forni, Diego, et al.
Publicado: (2021)

Evolution and Genetic Diversity of Primate Cytomegaloviruses
por: Cagliani, Rachele, et al.
Publicado: (2020)

Natural Selection at the Brush-Border: Adaptations to Carbohydrate Diets in Humans and Other Mammals
por: Pontremoli, Chiara, et al.
Publicado: (2015)

Ancient Evolution of Mammarenaviruses: Adaptation via Changes in the L Protein and No Evidence for Host–Virus Codivergence
por: Forni, Diego, et al.
Publicado: (2018)

Evolutionary rates of mammalian telomere-stability genes correlate with karyotype features and female germline expression
por: Pontremoli, Chiara, et al.
Publicado: (2018)

Multiple Selected Changes May Modulate the Molecular Interaction between Laverania RH5 and Primate Basigin
por: Forni, Diego, et al.
Publicado: (2018)

An APOBEC3 Mutational Signature in the Genomes of Human-Infecting Orthopoxviruses
por: Forni, Diego, et al.
Publicado: (2023)

The evolutionary history of genes involved in spoken and written language: beyond FOXP2
por: Mozzi, Alessandra, et al.
Publicado: (2016)

Past and ongoing adaptation of human cytomegalovirus to its host
por: Mozzi, Alessandra, et al.
Publicado: (2020)

Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions
por: Fumagalli, Matteo, et al.
Publicado: (2009)

Evolution of the orthopoxvirus core genome
por: Molteni, Cristian, et al.
Publicado: (2022)

Simplexviruses Successfully Adapt to Their Host by Fine-Tuning Immune Responses
por: Mozzi, Alessandra, et al.
Publicado: (2022)

Recombination and Positive Selection Differentially Shaped the Diversity of Betacoronavirus Subgenera
por: Forni, Diego, et al.
Publicado: (2020)

Genetic conflicts with Plasmodium parasites and functional constraints shape the evolution of erythrocyte cytoskeletal proteins
por: Sironi, Manuela, et al.
Publicado: (2018)

Evolutionary Analysis Provides Insight Into the Origin and Adaptation of HCV
por: Forni, Diego, et al.
Publicado: (2018)

The heptad repeat region is a major selection target in MERS-CoV and related coronaviruses
por: Forni, Diego, et al.
Publicado: (2015)

Ancient and Recent Selective Pressures Shaped Genetic Diversity at AIM2-Like Nucleic Acid Sensors
por: Cagliani, Rachele, et al.
Publicado: (2014)

Homology‐based classification of accessory proteins in coronavirus genomes uncovers extremely dynamic evolution of gene content
por: Forni, Diego, et al.
Publicado: (2022)

Selective events at individual sites underlie the evolution of monkeypox virus clades
por: Molteni, Cristian, et al.
Publicado: (2023)

Mammalian NPC1 genes may undergo positive selection and human polymorphisms associate with type 2 diabetes
por: Al-Daghri, Nasser M, et al.
Publicado: (2012)

Nonstructural Proteins Are Preferential Positive Selection Targets in Zika Virus and Related Flaviviruses
por: Sironi, Manuela, et al.
Publicado: (2016)

Origin and dispersal of Hepatitis E virus
por: Forni, Diego, et al.
Publicado: (2018)

Computational Inference of Selection Underlying the Evolution of the Novel Coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2
por: Cagliani, Rachele, et al.
Publicado: (2020)

Coding potential and sequence conservation of SARS-CoV-2 and related animal viruses
por: Cagliani, Rachele, et al.
Publicado: (2020)

Evolutionary insights into host–pathogen interactions from mammalian sequence data
por: Sironi, Manuela, et al.
Publicado: (2015)

Molecular Evolution of Human Coronavirus Genomes
por: Forni, Diego, et al.
Publicado: (2017)

The landscape of human genes involved in the immune response to parasitic worms
por: Fumagalli, Matteo, et al.
Publicado: (2010)

Genome-Wide Identification of Susceptibility Alleles for Viral Infections through a Population Genetics Approach
por: Fumagalli, Matteo, et al.
Publicado: (2010)

Gene function and expression level influence the insertion/fixation dynamics of distinct transposon families in mammalian introns
por: Sironi, Manuela, et al.
Publicado: (2006)

The substitution spectra of coronavirus genomes
por: Forni, Diego, et al.
Publicado: (2021)

Alternation between taxonomically divergent hosts is not the major determinant of flavivirus evolution
por: Pontremoli, Chiara, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_phfc7mok6c1eonbdnpr2melue0