Role of HDAC9-FoxO1 Axis in the Transcriptional Program Associated with Hepatic Gluconeogenesis

Histone deacetylase 9 (HDAC9) regulates hepatic gluconeogenesis by deacetylating Forkhead box O 1 (FoxO1). HDAC9 upregulation is involved in hepatitis C virus (HCV)-associated exaggerated gluconeogenesis. Herein, we found in addition to FoxO1, HDAC9 also regulates other gluconeogenic transcription f...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Jizheng, Zhang, Zhilei, Wang, Ning, Guo, Min, Chi, Xiumei, Pan, Yu, Jiang, Jing, Niu, Junqi, Ksimu, Sulaiman, Li, John Zhong, Chen, Xinwen, Wang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522426/
https://www.ncbi.nlm.nih.gov/pubmed/28733598
http://dx.doi.org/10.1038/s41598-017-06328-3

Ejemplares similares

Ejemplares similares