Cargando…

VGLL4 Selectively Represses YAP-Dependent Gene Induction and Tumorigenic Phenotypes in Breast Cancer

Members of the mammalian Vestigial-like (VGLL) family of transcriptional cofactors activate genes in response to a wide variety of environmental cues. Recently, VGLL proteins have been proposed to regulate key signaling networks involved in cancer development and progression. However, the biological...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yinglong, Shen, He, Withers, Henry G., Yang, Nuo, Denson, Kayla E., Mussell, Ashley L., Truskinovsky, Alexander, Fan, Qingyu, Gelman, Irwin H., Frangou, Costa, Zhang, Jianmin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522454/ https://www.ncbi.nlm.nih.gov/pubmed/28733631 http://dx.doi.org/10.1038/s41598-017-06227-7

Ejemplares similares

The Hippo Signaling Transducer TAZ Regulates Mammary Gland Morphogenesis and Carcinogen-induced Mammary Tumorigenesis
por: Denson, Kayla E., et al.
Publicado: (2018)

Loss of KIBRA function activates EGFR signaling by inducing AREG
por: Mussell, Ashley L., et al.
Publicado: (2018)

YAP–VGLL4 antagonism defines the major physiological function of the Hippo signaling effector YAP
por: Cai, Jing, et al.
Publicado: (2022)

Regulation of the Hippo signaling pathway by deubiquitinating enzymes in cancer
por: Mussell, Ashley, et al.
Publicado: (2019)

The Regulatory Role of KIBRA and PTPN14 in Hippo Signaling and Beyond
por: Wilson, Kayla E., et al.
Publicado: (2016)

Serotonin and YAP/VGLL4 Balance Correlated with Progression and Poor Prognosis of Hepatocellular Carcinoma
por: Shu, Bo, et al.
Publicado: (2018)

TEADs, Yap, Taz, Vgll4s transcription factors control the establishment of Left-Right asymmetry in zebrafish
por: Fillatre, Jonathan, et al.
Publicado: (2019)

Hybrid Schwannoma-Perineurioma Frequently Harbors VGLL3 Rearrangement
por: Dickson, Brendan C., et al.
Publicado: (2021)

VGLL4 Protects against Oxidized-LDL-Induced Endothelial Cell Dysfunction and Inflammation by Activating Hippo-YAP/TEAD1 Signaling Pathway
por: Xu, Kaicheng, et al.
Publicado: (2020)

Retracted: VGLL4 Protects against Oxidized-LDL-Induced Endothelial Cell Dysfunction and Inflammation by Activating Hippo-YAP/TEAD1 Signaling Pathway
por: of Inflammation, Mediators
Publicado: (2022)

S100A7 induction is repressed by YAP via the Hippo pathway in A431 cells
por: Li, Yunguang, et al.
Publicado: (2016)

USP1 Regulates TAZ Protein Stability Through Ubiquitin Modifications in Breast Cancer
por: Mussell, Ashley, et al.
Publicado: (2020)

VGLL2-NCOA2 leverages developmental programs for pediatric sarcomagenesis
por: Watson, Sarah, et al.
Publicado: (2023)

VGLL4 plays a critical role in heart valve development and homeostasis
por: Yu, Wei, et al.
Publicado: (2019)

VGLL4 promotes osteoblast differentiation by antagonizing TEADs-inhibited Runx2 transcription
por: Suo, Jinlong, et al.
Publicado: (2020)

Sox4 Expression Confers Bladder Cancer Stem Cell Properties and Predicts for Poor Patient Outcome
por: Shen, He, et al.
Publicado: (2015)

Depletion of VGLL4 Causes Perinatal Lethality without Affecting Myocardial Development
por: Sheldon, Caroline, et al.
Publicado: (2022)

Repression of YAP by NCTD disrupts NSCLC progression
por: Guo, Jiwei, et al.
Publicado: (2016)

VGLL3 is a prognostic biomarker and correlated with clinical pathologic features and immune infiltrates in stomach adenocarcinoma
por: Zhang, Lihua, et al.
Publicado: (2020)

VGLL3-regulated gene network as a promoter of sex biased autoimmune diseases
por: Liang, Yun, et al.
Publicado: (2016)

Linking vgll3 genotype and aggressive behaviour in juvenile Atlantic salmon (Salmo salar)
por: Bangura, Paul Bai, et al.
Publicado: (2022)

Development of supermale and all-male Atlantic salmon to research the vgll3 allele - puberty link
por: Fjelldal, Per Gunnar, et al.
Publicado: (2020)

VGLL4 and MENIN function as TEAD1 corepressors to block pancreatic β cell proliferation
por: Li, Feng, et al.
Publicado: (2023)

VGLL3 expression is associated with macrophage infiltration and predicts poor prognosis in epithelial ovarian cancer
por: Haque, Razaul, et al.
Publicado: (2023)

The influence of vgll3 genotypes on sea age at maturity is altered in farmed mowi strain Atlantic salmon
por: Ayllon, Fernando, et al.
Publicado: (2019)

A new perspective on the interaction between the Vg/VGLL1-3 proteins and the TEAD transcription factors
por: Mesrouze, Yannick, et al.
Publicado: (2020)

VGLL4 interacts with STAT3 to function as a tumor suppressor in triple-negative breast cancer
por: Song, Hongming, et al.
Publicado: (2019)

Deficiency of Vgll2 Gene Alters the Gene Expression Profiling of Skeletal Muscle Subjected to Mechanical Overload
por: Hitachi, Keisuke, et al.
Publicado: (2019)

VGLL3 is a mechanosensitive protein that promotes cardiac fibrosis through liquid–liquid phase separation
por: Horii, Yuma, et al.
Publicado: (2023)

VGLL4 targets a TCF4–TEAD4 complex to coregulate Wnt and Hippo signalling in colorectal cancer
por: Jiao, Shi, et al.
Publicado: (2017)

Molecular profiling and computational network analysis of TAZ-mediated mammary tumorigenesis identifies actionable therapeutic targets
por: Frangou, Costa, et al.
Publicado: (2014)

SU4312 Represses Glioma Progression by Inhibiting YAP and Inducing Sensitization to the Effect of Temozolomide
por: Wang, Xu, et al.
Publicado: (2022)

The vgll3 Locus Controls Age at Maturity in Wild and Domesticated Atlantic Salmon (Salmo salar L.) Males
por: Ayllon, Fernando, et al.
Publicado: (2015)

Vgll3 and the Hippo pathway are regulated in Sertoli cells upon entry and during puberty in Atlantic salmon testis
por: Kjærner-Semb, Erik, et al.
Publicado: (2018)

VGLL3 operates via TEAD1, TEAD3 and TEAD4 to influence myogenesis in skeletal muscle
por: Figeac, Nicolas, et al.
Publicado: (2019)

Genome-wide Interaction Study Implicates VGLL2 and Alcohol Exposure and PRL and Smoking in Orofacial Cleft Risk
por: Carlson, Jenna C., et al.
Publicado: (2022)

Regulation of type I interferon signature by VGLL3 in the fibroblast-like synoviocytes of rheumatoid arthritis patients via targeting the Hippo pathway
por: Du, Yu, et al.
Publicado: (2022)

Scutellarin Inhibits Proliferation, Invasion, and Tumorigenicity in Human Breast Cancer Cells by Regulating HIPPO-YAP Signaling Pathway
por: Hou, Lengchen, et al.
Publicado: (2017)

YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity
por: Yu, Olivia M, et al.
Publicado: (2018)

12-O-Tetradecanoylphorbol-13-acetate (TPA) is anti-tumorigenic in liver cancer cells via inhibiting YAP through AMOT
por: Zhu, Guoqing, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_sjlik2tqt4mdpteih2s81dsu31