Expression of the scaffold connector enhancer of kinase suppressor of Ras 1 (CNKSR1) is correlated with clinical outcome in pancreatic cancer

BACKGROUND: Despite the near universal occurrence of activating codon 12 KRAS somatic variants in pancreatic cancer, there is considerable heterogeneity in the molecular make-up, MAPK/ERK pathway activation states, and clinical outcome in this disease. We analyzed the expression levels of CNKSR1, a...

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Detalles Bibliográficos
Autores principales: Quadri, Humair S., Aiken, Taylor J., Allgaeuer, Michael, Moravec, Radim, Altekruse, Sean, Hussain, S. Perwez, Miettinen, Markku M., Hewitt, Stephen M., Rudloff, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522593/
https://www.ncbi.nlm.nih.gov/pubmed/28732488
http://dx.doi.org/10.1186/s12885-017-3481-4

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