Epigenetic memory of oxidative stress: does nephrilin exert its protective effects via Rac1?

AIM: Nephrilin peptide, a designed inhibitor of Rictor complex (mTORC2), exerts pleiotropic protective effects in metabolic, xenobiotic and traumatic stress models. Stress can generate enduring epigenetic changes in gene function. In this work we examine the possibility that nephrilin treatment prot...

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Detalles Bibliográficos
Autores principales: Mascarenhas, Desmond D, Herndon, David N, Arany, Istvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522666/
https://www.ncbi.nlm.nih.gov/pubmed/28761330
http://dx.doi.org/10.2147/BTT.S136188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522666/
https://www.ncbi.nlm.nih.gov/pubmed/28761330
http://dx.doi.org/10.2147/BTT.S136188

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