Cargando…
Epigenetic memory of oxidative stress: does nephrilin exert its protective effects via Rac1?
AIM: Nephrilin peptide, a designed inhibitor of Rictor complex (mTORC2), exerts pleiotropic protective effects in metabolic, xenobiotic and traumatic stress models. Stress can generate enduring epigenetic changes in gene function. In this work we examine the possibility that nephrilin treatment prot...
Autores principales: | Mascarenhas, Desmond D, Herndon, David N, Arany, Istvan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522666/ https://www.ncbi.nlm.nih.gov/pubmed/28761330 http://dx.doi.org/10.2147/BTT.S136188 |
Ejemplares similares
-
Transcriptional re-programming in rat central nervous system two weeks after burn trauma: the impact of nephrilin treatment on the expression of oxidative stress-related genes
por: Mascarenhas, Desmond D
Publicado: (2020) -
Positive effects of ferric iron on the systemic efficacy of nephrilin
peptide in burn trauma
por: Mascarenhas, Desmond D, et al.
Publicado: (2020) -
Covalent modification of nephrilin peptide with valproic acid increases its efficacy as a therapeutic in burn trauma
por: Mascarenhas, Desmond D., et al.
Publicado: (2020) -
Guanxintai Exerts Protective Effects on Ischemic Cardiomyocytes by Mitigating Oxidative Stress
por: Yang, Jing, et al.
Publicado: (2017) -
Tianma Gouteng Decoction Exerts Pregnancy-Protective Effects Against Preeclampsia via Regulation of Oxidative Stress and NO Signaling
por: Jin, Meiyuan, et al.
Publicado: (2022)