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Micro- and Nano-vesicles from First Trimester Human Placentae Carry Flt-1 and Levels Are Increased in Severe Preeclampsia
BACKGROUND/OBJECTIVES: Preeclampsia is a life-threatening hypertensive disease affecting 3–5% of pregnancies. While the pathogenesis of preeclampsia remains unclear, it is known that placenta-derived factors trigger the disease by activating maternal endothelial cells prior to the onset of clinical...
Autores principales: | Tong, Mancy, Chen, Qi, James, Joanna L., Stone, Peter R., Chamley, Lawrence W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522845/ https://www.ncbi.nlm.nih.gov/pubmed/28790977 http://dx.doi.org/10.3389/fendo.2017.00174 |
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