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Novel In Vitro Screening System Based on Differential Scanning Fluorimetry to Search for Small Molecules against the Disassembly or Assembly of HIV-1 Capsid Protein

Varieties of in vitro systems have been used to study biochemical properties of human immunodeficiency virus Gag-capsid protein (HIV Gag-CA). Recently, we have comparatively characterized HIV-1 and HIV-2 Gag-CA proteins using such technology, and have demonstrated that the NaCl-initiated CA-polymeri...

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Detalles Bibliográficos
Autores principales:	Miyazaki, Yasuyuki, Doi, Naoya, Koma, Takaaki, Adachi, Akio, Nomaguchi, Masako
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522879/ https://www.ncbi.nlm.nih.gov/pubmed/28791001 http://dx.doi.org/10.3389/fmicb.2017.01413

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