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Mint3-mediated L1CAM expression in fibroblasts promotes cancer cell proliferation via integrin α5β1 and tumour growth

Fibroblasts are some of the major cells in tumour tissues that influence tumour progression and drug resistance. However, our understanding on fibroblast-mediated tumour malignancy remains incomplete. Munc18-1-interacting protein 3 (Mint3) is known as an activator of hypoxia-inducible factor-1 (HIF-...

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Detalles Bibliográficos
Autores principales: Nakaoka, H J, Tanei, Z, Hara, T, Weng, J S, Kanamori, A, Hayashi, T, Sato, H, Orimo, A, Otsuji, K, Tada, K, Morikawa, T, Sasaki, T, Fukayama, M, Seiki, M, Murakami, Y, Sakamoto, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523060/
https://www.ncbi.nlm.nih.gov/pubmed/28504692
http://dx.doi.org/10.1038/oncsis.2017.27