The prohibitin-repressive interaction with E2F1 is rapidly inhibited by androgen signalling in prostate cancer cells

Prohibitin (PHB) is a tumour suppressor molecule with pleiotropic activities across several cellular compartments including mitochondria, cell membrane and the nucleus. PHB and the steroid-activated androgen receptor (AR) have an interplay where AR downregulates PHB, and PHB represses AR. Additional...

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Detalles Bibliográficos
Autores principales: Koushyar, S, Economides, G, Zaat, S, Jiang, W, Bevan, C L, Dart, D A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523065/
https://www.ncbi.nlm.nih.gov/pubmed/28504694
http://dx.doi.org/10.1038/oncsis.2017.32

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