TRPV4 plays a role in breast cancer cell migration via Ca(2+)-dependent activation of AKT and downregulation of E-cadherin cell cortex protein

TRPV4 belongs to the ‘Transient Receptor Potential’ (TRP) superfamily. It has been identified to profoundly affect a variety of physiological processes, including nociception, heat sensation and inflammation. Unlike other TRP superfamily channels, its role in cancers are unknown until recently when...

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Detalles Bibliográficos
Autores principales: Lee, W H, Choong, L Y, Jin, T H, Mon, N N, Chong, S, Liew, C S, Putti, T, Lu, S Y, Harteneck, C, Lim, Y P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523072/
https://www.ncbi.nlm.nih.gov/pubmed/28530703
http://dx.doi.org/10.1038/oncsis.2017.39

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