AKT is indispensable for coordinating Par-4/JNK cross talk in p21 downmodulation during ER stress

The double-edged role of p21 to command survival and apoptosis is emerging. The current investigation highlights ER stress-mediated JNK activation that plausibly triggers cell death by attenuating endogenous p21 level. Here, we demonstrated that ER stress activator 3-AWA diminishes the p21 levels in...

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Detalles Bibliográficos
Autores principales: Rasool, R U, Nayak, D, Chakraborty, S, Faheem, M M, Rah, B, Mahajan, P, Gopinath, V, Katoch, A, Iqra, Z, Yousuf, S K, Mukherjee, D, Kumar, L D, Nargotra, A, Goswami, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523074/
https://www.ncbi.nlm.nih.gov/pubmed/28530706
http://dx.doi.org/10.1038/oncsis.2017.41

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