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Inhibition of human immunodeficiency virus type-1 (HIV-1) glycoprotein-mediated cell-cell fusion by immunor (IM28)

BACKGROUND: Immunor (IM28), an analog of dehydroepiandrosterone (DHEA), inhibits human immunodeficiency virus type-1 (HIV-1) by inhibiting reverse transcriptase. We assessed the ability of IM28 to inhibit the cell-cell fusion mediated by HIV envelope glycoprotein in an in vitro system. For this purp...

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Detalles Bibliográficos
Autores principales: Mavoungou, Donatien, Poaty-Mavoungou, Virginie, Akoume, Marie-Yvonne, Ongali, Brice, Mavoungou, Elie
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC552330/
https://www.ncbi.nlm.nih.gov/pubmed/15707492
http://dx.doi.org/10.1186/1743-422X-2-9