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CYP1B1 Activates Wnt/β-Catenin Signaling through Suppression of Herc5-Mediated ISGylation for Protein Degradation on β-Catenin in HeLa Cells

Cytochrome P450 1B1 (CYP1B1) acts as a hydroxylase for estrogen and activates potential carcinogens. Moreover, its expression in tumor tissues is much higher than that in normal tissues. Despite this association between CYP1B1 and cancer, the detailed molecular mechanism of CYP1B1 on cancer progress...

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Detalles Bibliográficos
Autores principales:	Park, Young-Shin, Kwon, Yeo-Jung, Chun, Young-Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society of Toxicology 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523555/ https://www.ncbi.nlm.nih.gov/pubmed/28744352 http://dx.doi.org/10.5487/TR.2017.33.3.211

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