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TMEM39A and Human Diseases: A Brief Review

Transmembrane Protein 39A (TMEM39A) is a member of TMEM family. The understanding about this protein is still limited. The earlier studies indicated that TMEM39A was a key mediator of autoimmune disease. TMEM39A seems to be involved in systemic lupus erythematosus and multiple sclerosis in numerous...

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Autores principales: Tran, Quangdon, Park, Jisoo, Lee, Hyunji, Hong, Youngeun, Hong, Suntaek, Park, Sungjin, Park, Jongsun, Kim, Seon-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Toxicology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523561/
https://www.ncbi.nlm.nih.gov/pubmed/28744351
http://dx.doi.org/10.5487/TR.2017.33.3.205
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author Tran, Quangdon
Park, Jisoo
Lee, Hyunji
Hong, Youngeun
Hong, Suntaek
Park, Sungjin
Park, Jongsun
Kim, Seon-Hwan
author_facet Tran, Quangdon
Park, Jisoo
Lee, Hyunji
Hong, Youngeun
Hong, Suntaek
Park, Sungjin
Park, Jongsun
Kim, Seon-Hwan
author_sort Tran, Quangdon
collection PubMed
description Transmembrane Protein 39A (TMEM39A) is a member of TMEM family. The understanding about this protein is still limited. The earlier studies indicated that TMEM39A was a key mediator of autoimmune disease. TMEM39A seems to be involved in systemic lupus erythematosus and multiple sclerosis in numerous of populations. All of these works stop at insufficient information by using gene functioning methods such as: Genome-wide association studies (GWASs) and/or follow-up study. It is the fact that the less understood of TMEM39A actually is the attraction to the scientist in near future. In this review the current knowledge about TMEM39A and its possible roles in cell biology, physiology and pathology will be described.
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spelling pubmed-55235612017-07-25 TMEM39A and Human Diseases: A Brief Review Tran, Quangdon Park, Jisoo Lee, Hyunji Hong, Youngeun Hong, Suntaek Park, Sungjin Park, Jongsun Kim, Seon-Hwan Toxicol Res Review Article Transmembrane Protein 39A (TMEM39A) is a member of TMEM family. The understanding about this protein is still limited. The earlier studies indicated that TMEM39A was a key mediator of autoimmune disease. TMEM39A seems to be involved in systemic lupus erythematosus and multiple sclerosis in numerous of populations. All of these works stop at insufficient information by using gene functioning methods such as: Genome-wide association studies (GWASs) and/or follow-up study. It is the fact that the less understood of TMEM39A actually is the attraction to the scientist in near future. In this review the current knowledge about TMEM39A and its possible roles in cell biology, physiology and pathology will be described. Korean Society of Toxicology 2017-07 2017-07-15 /pmc/articles/PMC5523561/ /pubmed/28744351 http://dx.doi.org/10.5487/TR.2017.33.3.205 Text en Copyright © 2017 The Korean Society Of Toxicology http://creativecommons.org/licenses/by-nc/3.0 This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Tran, Quangdon
Park, Jisoo
Lee, Hyunji
Hong, Youngeun
Hong, Suntaek
Park, Sungjin
Park, Jongsun
Kim, Seon-Hwan
TMEM39A and Human Diseases: A Brief Review
title TMEM39A and Human Diseases: A Brief Review
title_full TMEM39A and Human Diseases: A Brief Review
title_fullStr TMEM39A and Human Diseases: A Brief Review
title_full_unstemmed TMEM39A and Human Diseases: A Brief Review
title_short TMEM39A and Human Diseases: A Brief Review
title_sort tmem39a and human diseases: a brief review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523561/
https://www.ncbi.nlm.nih.gov/pubmed/28744351
http://dx.doi.org/10.5487/TR.2017.33.3.205
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