Genetic and Functional Associations with Decreased Anti-inflammatory Tumor Necrosis Factor Alpha Induced Protein 3 in Macrophages from Subjects with Axial Spondyloarthritis

OBJECTIVE: Tumor necrosis factor alpha-induced protein 3 (TNFAIP3) is an anti-inflammatory protein implicated in multiple autoimmune and rheumatologic conditions. We hypothesized that lower levels of TNFAIP3 contributes to excessive cytokine production in response to inflammatory stimuli in axial sp...

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Detalles Bibliográficos
Autores principales: Liu, Yiping, Ye, Zhan, Li, Xiang, Anderson, Jennifer L., Khan, Mike, DaSilva, Douglas, Baron, Marissa, Wilson, Deborah, Bocoun, Vera, Ivacic, Lynn C., Schrodi, Steven J., Smith, Judith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523649/
https://www.ncbi.nlm.nih.gov/pubmed/28791018
http://dx.doi.org/10.3389/fimmu.2017.00860

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