Cargando…
Obesity prevalence and related risk of comorbidities among HIV+ patients attending a New England ambulatory centre
BACKGROUND: Human immunodeficiency virus infection and obesity are pro‐inflammatory conditions that, when occurring together, may pose a synergistic risk for diabetes and cardiovascular disease. PURPOSE: The aim of the current study was (i) to document the prevalence of obesity in HIV+ patients trea...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523689/ https://www.ncbi.nlm.nih.gov/pubmed/28835853 http://dx.doi.org/10.1002/osp4.38 |
_version_ | 1783252358864568320 |
---|---|
author | Becofsky, Katie M. Wing, Edward J. Wing, Rena R. Richards, Kathryn E. Gillani, Fizza S. |
author_facet | Becofsky, Katie M. Wing, Edward J. Wing, Rena R. Richards, Kathryn E. Gillani, Fizza S. |
author_sort | Becofsky, Katie M. |
collection | PubMed |
description | BACKGROUND: Human immunodeficiency virus infection and obesity are pro‐inflammatory conditions that, when occurring together, may pose a synergistic risk for diabetes and cardiovascular disease. PURPOSE: The aim of the current study was (i) to document the prevalence of obesity in HIV+ patients treated at the Miriam Hospital Immunology Center (Providence, RI) and (ii) to investigate the relationship between obesity and comorbidities. METHODS: The study population consisted of 1,489 HIV+ adults (70% men; average age 48 ± 11 years) treated between 01/01/2012 and 06/30/2014. Separate logistic regressions tested the associations between overweight and obesity and comorbid diagnoses (diabetes, hypertension and cardiovascular disease), as compared with normal weight. Covariates included age, gender and smoking status. RESULTS: Approximately 37% of patients were overweight (body mass index 25.0–29.9), and an additional 28% were obese (body mass index ≥30.0). Obesity was associated with higher odds of comorbid diabetes (OR = 3.26, CI = 1.98–5.39) and hypertension (OR = 2.11, CI = 1.49–2.98). There was no significant association between obesity and the presence of cardiovascular disease (OR = 1.12, CI = 0.66–1.90). Overweight was associated only with higher odds of comorbid diabetes (OR = 1.72; CI = 1.02–2.88). CONCLUSION: Our findings demonstrate a heightened risk of comorbidities in overweight and obese HIV+ patients. Future studies should investigate whether weight loss interventions for this population can reduce cardiovascular and metabolic risk factors as they do in other populations. |
format | Online Article Text |
id | pubmed-5523689 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-55236892017-08-21 Obesity prevalence and related risk of comorbidities among HIV+ patients attending a New England ambulatory centre Becofsky, Katie M. Wing, Edward J. Wing, Rena R. Richards, Kathryn E. Gillani, Fizza S. Obes Sci Pract Original Articles BACKGROUND: Human immunodeficiency virus infection and obesity are pro‐inflammatory conditions that, when occurring together, may pose a synergistic risk for diabetes and cardiovascular disease. PURPOSE: The aim of the current study was (i) to document the prevalence of obesity in HIV+ patients treated at the Miriam Hospital Immunology Center (Providence, RI) and (ii) to investigate the relationship between obesity and comorbidities. METHODS: The study population consisted of 1,489 HIV+ adults (70% men; average age 48 ± 11 years) treated between 01/01/2012 and 06/30/2014. Separate logistic regressions tested the associations between overweight and obesity and comorbid diagnoses (diabetes, hypertension and cardiovascular disease), as compared with normal weight. Covariates included age, gender and smoking status. RESULTS: Approximately 37% of patients were overweight (body mass index 25.0–29.9), and an additional 28% were obese (body mass index ≥30.0). Obesity was associated with higher odds of comorbid diabetes (OR = 3.26, CI = 1.98–5.39) and hypertension (OR = 2.11, CI = 1.49–2.98). There was no significant association between obesity and the presence of cardiovascular disease (OR = 1.12, CI = 0.66–1.90). Overweight was associated only with higher odds of comorbid diabetes (OR = 1.72; CI = 1.02–2.88). CONCLUSION: Our findings demonstrate a heightened risk of comorbidities in overweight and obese HIV+ patients. Future studies should investigate whether weight loss interventions for this population can reduce cardiovascular and metabolic risk factors as they do in other populations. John Wiley and Sons Inc. 2016-05-31 /pmc/articles/PMC5523689/ /pubmed/28835853 http://dx.doi.org/10.1002/osp4.38 Text en © 2016 The Authors. Obesity Science & Practice published by John Wiley & Sons Ltd, World Obesity and The Obesity Society. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Original Articles Becofsky, Katie M. Wing, Edward J. Wing, Rena R. Richards, Kathryn E. Gillani, Fizza S. Obesity prevalence and related risk of comorbidities among HIV+ patients attending a New England ambulatory centre |
title | Obesity prevalence and related risk of comorbidities among HIV+ patients attending a New England ambulatory centre |
title_full | Obesity prevalence and related risk of comorbidities among HIV+ patients attending a New England ambulatory centre |
title_fullStr | Obesity prevalence and related risk of comorbidities among HIV+ patients attending a New England ambulatory centre |
title_full_unstemmed | Obesity prevalence and related risk of comorbidities among HIV+ patients attending a New England ambulatory centre |
title_short | Obesity prevalence and related risk of comorbidities among HIV+ patients attending a New England ambulatory centre |
title_sort | obesity prevalence and related risk of comorbidities among hiv+ patients attending a new england ambulatory centre |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523689/ https://www.ncbi.nlm.nih.gov/pubmed/28835853 http://dx.doi.org/10.1002/osp4.38 |
work_keys_str_mv | AT becofskykatiem obesityprevalenceandrelatedriskofcomorbiditiesamonghivpatientsattendinganewenglandambulatorycentre AT wingedwardj obesityprevalenceandrelatedriskofcomorbiditiesamonghivpatientsattendinganewenglandambulatorycentre AT wingrenar obesityprevalenceandrelatedriskofcomorbiditiesamonghivpatientsattendinganewenglandambulatorycentre AT richardskathryne obesityprevalenceandrelatedriskofcomorbiditiesamonghivpatientsattendinganewenglandambulatorycentre AT gillanifizzas obesityprevalenceandrelatedriskofcomorbiditiesamonghivpatientsattendinganewenglandambulatorycentre |