Tissue Transglutaminase Modulates Vascular Stiffness and Function Through Crosslinking‐Dependent and Crosslinking‐Independent Functions

BACKGROUND: The structural elements of the vascular wall, namely, extracellular matrix and smooth muscle cells (SMCs), contribute to the overall stiffness of the vessel. In this study, we examined the crosslinking‐dependent and crosslinking‐independent roles of tissue transglutaminase (TG2) in vascu...

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Detalles Bibliográficos
Autores principales: Steppan, Jochen, Bergman, Yehudit, Viegas, Kayla, Armstrong, Dinani, Tan, Siqi, Wang, Huilei, Melucci, Sean, Hori, Daijiro, Park, Sung Yong, Barreto, Sebastian F., Isak, Abraham, Jandu, Sandeep, Flavahan, Nicholas, Butlin, Mark, An, Steven S., Avolio, Alberto, Berkowitz, Dan E., Halushka, Marc K., Santhanam, Lakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523743/
https://www.ncbi.nlm.nih.gov/pubmed/28159817
http://dx.doi.org/10.1161/JAHA.116.004161

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