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Iron Concentration in Deep Gray Matter Structures is Associated with Worse Visual Memory Performance in Healthy Young Adults
Abnormally high deposition of iron can contribute to neurodegenerative disorders with cognitive impairment. Since previous studies investigating cognition-brain iron accumulation relationships focused on elderly people, our aim was to explore the association between iron concentration in subcortical...
| Autores principales: | , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
IOS Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523837/ https://www.ncbi.nlm.nih.gov/pubmed/28671115 http://dx.doi.org/10.3233/JAD-170118 |
| _version_ | 1783252377536561152 |
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| author | Darnai, Gergely Nagy, Szilvia Anett Horváth, Réka Ács, Péter Perlaki, Gábor Orsi, Gergely Kovács, Norbert Altbäcker, Anna Plózer, Enikő Tényi, Dalma Weintraut, Rita Schwarcz, Attila John, Flóra Varga, Eszter Bereczkei, Tamás Clemens, Zsófia Komoly, Sámuel Janszky, József |
| author_facet | Darnai, Gergely Nagy, Szilvia Anett Horváth, Réka Ács, Péter Perlaki, Gábor Orsi, Gergely Kovács, Norbert Altbäcker, Anna Plózer, Enikő Tényi, Dalma Weintraut, Rita Schwarcz, Attila John, Flóra Varga, Eszter Bereczkei, Tamás Clemens, Zsófia Komoly, Sámuel Janszky, József |
| author_sort | Darnai, Gergely |
| collection | PubMed |
| description | Abnormally high deposition of iron can contribute to neurodegenerative disorders with cognitive impairment. Since previous studies investigating cognition-brain iron accumulation relationships focused on elderly people, our aim was to explore the association between iron concentration in subcortical nuclei and two types of memory performances in a healthy young population. Gender difference was found only in the globus pallidus. Our results showed that iron load characterized by R2* value on the MRI in the caudate and putamen was related to visual memory, while verbal memory was unrelated to iron concentration. |
| format | Online Article Text |
| id | pubmed-5523837 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2017 |
| publisher | IOS Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-55238372017-08-16 Iron Concentration in Deep Gray Matter Structures is Associated with Worse Visual Memory Performance in Healthy Young Adults Darnai, Gergely Nagy, Szilvia Anett Horváth, Réka Ács, Péter Perlaki, Gábor Orsi, Gergely Kovács, Norbert Altbäcker, Anna Plózer, Enikő Tényi, Dalma Weintraut, Rita Schwarcz, Attila John, Flóra Varga, Eszter Bereczkei, Tamás Clemens, Zsófia Komoly, Sámuel Janszky, József J Alzheimers Dis Research Article Abnormally high deposition of iron can contribute to neurodegenerative disorders with cognitive impairment. Since previous studies investigating cognition-brain iron accumulation relationships focused on elderly people, our aim was to explore the association between iron concentration in subcortical nuclei and two types of memory performances in a healthy young population. Gender difference was found only in the globus pallidus. Our results showed that iron load characterized by R2* value on the MRI in the caudate and putamen was related to visual memory, while verbal memory was unrelated to iron concentration. IOS Press 2017-07-17 /pmc/articles/PMC5523837/ /pubmed/28671115 http://dx.doi.org/10.3233/JAD-170118 Text en © 2017 – IOS Press and the authors. All rights reserved https://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) License (https://creativecommons.org/licenses/by-nc/4.0/) , which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Research Article Darnai, Gergely Nagy, Szilvia Anett Horváth, Réka Ács, Péter Perlaki, Gábor Orsi, Gergely Kovács, Norbert Altbäcker, Anna Plózer, Enikő Tényi, Dalma Weintraut, Rita Schwarcz, Attila John, Flóra Varga, Eszter Bereczkei, Tamás Clemens, Zsófia Komoly, Sámuel Janszky, József Iron Concentration in Deep Gray Matter Structures is Associated with Worse Visual Memory Performance in Healthy Young Adults |
| title | Iron Concentration in Deep Gray Matter Structures is Associated with Worse Visual Memory Performance in Healthy Young Adults |
| title_full | Iron Concentration in Deep Gray Matter Structures is Associated with Worse Visual Memory Performance in Healthy Young Adults |
| title_fullStr | Iron Concentration in Deep Gray Matter Structures is Associated with Worse Visual Memory Performance in Healthy Young Adults |
| title_full_unstemmed | Iron Concentration in Deep Gray Matter Structures is Associated with Worse Visual Memory Performance in Healthy Young Adults |
| title_short | Iron Concentration in Deep Gray Matter Structures is Associated with Worse Visual Memory Performance in Healthy Young Adults |
| title_sort | iron concentration in deep gray matter structures is associated with worse visual memory performance in healthy young adults |
| topic | Research Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523837/ https://www.ncbi.nlm.nih.gov/pubmed/28671115 http://dx.doi.org/10.3233/JAD-170118 |
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