Robust Generation of Quiescent Porcine Valvular Interstitial Cell Cultures

BACKGROUND: Valvular interstitial cells (VICs) in the healthy aortic valve leaflet exhibit a quiescent phenotype, with <5% of VICs exhibiting an activated phenotype. Yet, in vitro culture of VICs on tissue culture polystyrene surfaces in standard growth medium results in rapid transformation to a...

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Detalles Bibliográficos
Autores principales: Porras, Ana M., van Engeland, Nicole C. A., Marchbanks, Evelyn, McCormack, Ann, Bouten, Carlijn V. C., Yacoub, Magdi H., Latif, Najma, Masters, Kristyn S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524027/
https://www.ncbi.nlm.nih.gov/pubmed/28292746
http://dx.doi.org/10.1161/JAHA.116.005041

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