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Metabolic Mediators of the Effects of Family History and Genetic Risk Score on Coronary Heart Disease—Findings From the Malmö Diet and Cancer Study

BACKGROUND: Family history of coronary heart disease (CHD) as well as genetic predisposition to CHD assessed by a genetic risk score (GRS) are predictors of CHD risk. It is, however, uncertain to what extent these risk predictors are mediated by major metabolic pathways. METHODS AND RESULTS: Total e...

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Detalles Bibliográficos
Autores principales: Fritz, Josef, Shiffman, Dov, Melander, Olle, Tada, Hayato, Ulmer, Hanno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524031/
https://www.ncbi.nlm.nih.gov/pubmed/28320750
http://dx.doi.org/10.1161/JAHA.116.005254