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Post‐Myocardial Infarction T‐tubules Form Enlarged Branched Structures With Dysregulation of Junctophilin‐2 and Bridging Integrator 1 (BIN‐1)

BACKGROUND: Heart failure is a common secondary complication following a myocardial infarction (MI), characterized by impaired cardiac contraction and t‐tubule (t‐t) loss. However, post‐MI nano‐scale morphological changes to the remaining t‐ts are poorly understood. METHOD AND RESULTS: We utilized a...

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Detalles Bibliográficos
Autores principales: Pinali, Christian, Malik, Nadim, Davenport, J. Bernard, Allan, Laurence J., Murfitt, Lucy, Iqbal, Mohammad M., Boyett, Mark R., Wright, Elizabeth J., Walker, Rachel, Zhang, Yu, Dobryznski, Halina, Holt, Cathy M., Kitmitto, Ashraf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524063/
https://www.ncbi.nlm.nih.gov/pubmed/28473402
http://dx.doi.org/10.1161/JAHA.116.004834