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Post‐Myocardial Infarction T‐tubules Form Enlarged Branched Structures With Dysregulation of Junctophilin‐2 and Bridging Integrator 1 (BIN‐1)
BACKGROUND: Heart failure is a common secondary complication following a myocardial infarction (MI), characterized by impaired cardiac contraction and t‐tubule (t‐t) loss. However, post‐MI nano‐scale morphological changes to the remaining t‐ts are poorly understood. METHOD AND RESULTS: We utilized a...
Autores principales: | Pinali, Christian, Malik, Nadim, Davenport, J. Bernard, Allan, Laurence J., Murfitt, Lucy, Iqbal, Mohammad M., Boyett, Mark R., Wright, Elizabeth J., Walker, Rachel, Zhang, Yu, Dobryznski, Halina, Holt, Cathy M., Kitmitto, Ashraf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524063/ https://www.ncbi.nlm.nih.gov/pubmed/28473402 http://dx.doi.org/10.1161/JAHA.116.004834 |
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