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An essential EBV latent antigen 3C binds Bcl6 for targeted degradation and cell proliferation

The latent EBV nuclear antigen 3C (EBNA3C) is required for transformation of primary human B lymphocytes. Most mature B-cell malignancies originate from malignant transformation of germinal center (GC) B-cells. The GC reaction appears to have a role in malignant transformation, in which a major play...

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Detalles Bibliográficos
Autores principales:	Pei, Yonggang, Banerjee, Shuvomoy, Jha, Hem Chandra, Sun, Zhiguo, Robertson, Erle S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524291/ https://www.ncbi.nlm.nih.gov/pubmed/28738086 http://dx.doi.org/10.1371/journal.ppat.1006500

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