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Zebrafish slc30a10 deficiency revealed a novel compensatory mechanism of Atp2c1 in maintaining manganese homeostasis
Recent studies found that mutations in the human SLC30A10 gene, which encodes a manganese (Mn) efflux transporter, are associated with hypermanganesemia with dystonia, polycythemia, and cirrhosis (HMDPC). However, the relationship between Mn metabolism and HMDPC is poorly understood, and no specific...
Autores principales: | Xia, Zhidan, Wei, Jiayu, Li, Yingniang, Wang, Jia, Li, Wenwen, Wang, Kai, Hong, Xiaoli, Zhao, Lu, Chen, Caiyong, Min, Junxia, Wang, Fudi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524415/ https://www.ncbi.nlm.nih.gov/pubmed/28692648 http://dx.doi.org/10.1371/journal.pgen.1006892 |
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