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Self-propagating, protease-resistant, recombinant prion protein conformers with or without in vivo pathogenicity

Prions, characterized by self-propagating protease-resistant prion protein (PrP) conformations, are agents causing prion disease. Recent studies generated several such self-propagating protease-resistant recombinant PrP (rPrP-res) conformers. While some cause prion disease, others fail to induce any...

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Detalles Bibliográficos
Autores principales:	Wang, Fei, Wang, Xinhe, Orrú, Christina D., Groveman, Bradley R., Surewicz, Krystyna, Abskharon, Romany, Imamura, Morikazu, Yokoyama, Takashi, Kim, Yong-Sun, Vander Stel, Kayla J., Sinniah, Kumar, Priola, Suzette A., Surewicz, Witold K., Caughey, Byron, Ma, Jiyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524416/ https://www.ncbi.nlm.nih.gov/pubmed/28704563 http://dx.doi.org/10.1371/journal.ppat.1006491

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