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EGFR or PD-L1 decision for first line therapy in a case series of EGFR positive and PD-L1 >50%

Targeted therapies are on the market for the past five years and recently pembrolizumab was approved as first line treatment for patients with PD-L1 >50%. We present three cases of patients which had epidermal growth factor receptor positive expression and programmed death-ligand 1 (PD-L1), PD-L1...

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Autores principales: Zarogoulidis, Paul, Chinelis, Panos, Efthymiou, Christofors, Athanasiadou, Anastasia, Mpikos, Vasilis, Papatsibas, George, Papadopoulos, Vasilis, Maragouli, Elena, Huang, Haidong, Trakada, Georgia, Kallianos, Anastasios, Veletza, Lemonia, Hohenforst-Schmidt, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524632/
https://www.ncbi.nlm.nih.gov/pubmed/28761805
http://dx.doi.org/10.1016/j.rmcr.2017.05.010
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author Zarogoulidis, Paul
Chinelis, Panos
Efthymiou, Christofors
Athanasiadou, Anastasia
Mpikos, Vasilis
Papatsibas, George
Papadopoulos, Vasilis
Maragouli, Elena
Huang, Haidong
Trakada, Georgia
Kallianos, Anastasios
Veletza, Lemonia
Hohenforst-Schmidt, Wolfgang
author_facet Zarogoulidis, Paul
Chinelis, Panos
Efthymiou, Christofors
Athanasiadou, Anastasia
Mpikos, Vasilis
Papatsibas, George
Papadopoulos, Vasilis
Maragouli, Elena
Huang, Haidong
Trakada, Georgia
Kallianos, Anastasios
Veletza, Lemonia
Hohenforst-Schmidt, Wolfgang
author_sort Zarogoulidis, Paul
collection PubMed
description Targeted therapies are on the market for the past five years and recently pembrolizumab was approved as first line treatment for patients with PD-L1 >50%. We present three cases of patients which had epidermal growth factor receptor positive expression and programmed death-ligand 1 (PD-L1), PD-L1 >50% overexpression.
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spelling pubmed-55246322017-07-31 EGFR or PD-L1 decision for first line therapy in a case series of EGFR positive and PD-L1 >50% Zarogoulidis, Paul Chinelis, Panos Efthymiou, Christofors Athanasiadou, Anastasia Mpikos, Vasilis Papatsibas, George Papadopoulos, Vasilis Maragouli, Elena Huang, Haidong Trakada, Georgia Kallianos, Anastasios Veletza, Lemonia Hohenforst-Schmidt, Wolfgang Respir Med Case Rep Case Report Targeted therapies are on the market for the past five years and recently pembrolizumab was approved as first line treatment for patients with PD-L1 >50%. We present three cases of patients which had epidermal growth factor receptor positive expression and programmed death-ligand 1 (PD-L1), PD-L1 >50% overexpression. Elsevier 2017-05-30 /pmc/articles/PMC5524632/ /pubmed/28761805 http://dx.doi.org/10.1016/j.rmcr.2017.05.010 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Zarogoulidis, Paul
Chinelis, Panos
Efthymiou, Christofors
Athanasiadou, Anastasia
Mpikos, Vasilis
Papatsibas, George
Papadopoulos, Vasilis
Maragouli, Elena
Huang, Haidong
Trakada, Georgia
Kallianos, Anastasios
Veletza, Lemonia
Hohenforst-Schmidt, Wolfgang
EGFR or PD-L1 decision for first line therapy in a case series of EGFR positive and PD-L1 >50%
title EGFR or PD-L1 decision for first line therapy in a case series of EGFR positive and PD-L1 >50%
title_full EGFR or PD-L1 decision for first line therapy in a case series of EGFR positive and PD-L1 >50%
title_fullStr EGFR or PD-L1 decision for first line therapy in a case series of EGFR positive and PD-L1 >50%
title_full_unstemmed EGFR or PD-L1 decision for first line therapy in a case series of EGFR positive and PD-L1 >50%
title_short EGFR or PD-L1 decision for first line therapy in a case series of EGFR positive and PD-L1 >50%
title_sort egfr or pd-l1 decision for first line therapy in a case series of egfr positive and pd-l1 >50%
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524632/
https://www.ncbi.nlm.nih.gov/pubmed/28761805
http://dx.doi.org/10.1016/j.rmcr.2017.05.010
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