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Genome editing abrogates angiogenesis in vivo

Angiogenesis, in which vascular endothelial growth factor receptor (VEGFR) 2 plays an essential role, is associated with a variety of human diseases including proliferative diabetic retinopathy and wet age-related macular degeneration. Here we report that a system of adeno-associated virus (AAV)-med...

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Detalles Bibliográficos
Autores principales: Huang, Xionggao, Zhou, Guohong, Wu, Wenyi, Duan, Yajian, Ma, Gaoen, Song, Jingyuan, Xiao, Ru, Vandenberghe, Luk, Zhang, Feng, D’Amore, Patricia A., Lei, Hetian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524639/
https://www.ncbi.nlm.nih.gov/pubmed/28740073
http://dx.doi.org/10.1038/s41467-017-00140-3