Microglial depletion and activation: A [(11)C]PBR28 PET study in nonhuman primates

BACKGROUND: The 18-kDa translocator protein (TSPO) is an important target for assessing neuroimmune function in brain with positron-emission tomography (PET) imaging. The goal of this work was to assess two [(11)C]PBR28 imaging paradigms for measuring dynamic microglia changes in Macaca mulatta. MET...

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Detalles Bibliográficos
Autores principales: Hillmer, Ansel T., Holden, Daniel, Fowles, Krista, Nabulsi, Nabeel, West, Brian L., Carson, Richard E., Cosgrove, Kelly P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Preliminary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524658/
https://www.ncbi.nlm.nih.gov/pubmed/28741281
http://dx.doi.org/10.1186/s13550-017-0305-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524658/
https://www.ncbi.nlm.nih.gov/pubmed/28741281
http://dx.doi.org/10.1186/s13550-017-0305-0

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