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Potentiation of 17β-estradiol synthesis in the brain and elongation of seizure latency through dietary supplementation with docosahexaenoic acid

Several studies have shown that docosahexaenoic acid (DHA) attenuates epileptic seizures; however, the molecular mechanism by which it achieves this effect is still largely unknown. DHA stimulates the retinoid X receptor, which reportedly regulates the expression of cytochrome P450 aromatase (P450ar...

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Detalles Bibliográficos
Autores principales:	Ishihara, Yasuhiro, Itoh, Kouichi, Tanaka, Miki, Tsuji, Mayumi, Kawamoto, Toshihiro, Kawato, Suguru, Vogel, Christoph F. A., Yamazaki, Takeshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524681/ https://www.ncbi.nlm.nih.gov/pubmed/28740157 http://dx.doi.org/10.1038/s41598-017-06630-0

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