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Role of p66shc in skeletal muscle function
p66shc is a growth factor adaptor protein that contributes to mitochondrial ROS production. p66shc is involved in insulin signaling and its deletion exerts a protective effect against diet-induced obesity. In light of the role of skeletal muscle activity in the control of systemic metabolism and obe...
Autores principales: | Granatiero, Veronica, Gherardi, Gaia, Vianello, Matteo, Salerno, Elsa, Zecchini, Erika, Toniolo, Luana, Pallafacchina, Giorgia, Murgia, Marta, Blaauw, Bert, Rizzuto, Rosario, Mammucari, Cristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524746/ https://www.ncbi.nlm.nih.gov/pubmed/28740219 http://dx.doi.org/10.1038/s41598-017-06363-0 |
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