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Angiopoietin-like 4 induces a β-catenin-mediated upregulation of ID3 in fibroblasts to reduce scar collagen expression
In adult skin wounds, collagen expression rapidly re-establishes the skin barrier, although the resultant scar is aesthetically and functionally inferior to unwounded tissue. Although TGFβ signaling and fibroblasts are known to be responsible for scar-associated collagen production, there are curren...
Autores principales: | Teo, Ziqiang, Chan, Jeremy Soon Kiat, Chong, Han Chung, Sng, Ming Keat, Choo, Chee Chong, Phua, Glendon Zhi Ming, Teo, Daniel Jin Rong, Zhu, Pengcheng, Choong, Cleo, Wong, Marcus Thien Chong, Tan, Nguan Soon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524754/ https://www.ncbi.nlm.nih.gov/pubmed/28740178 http://dx.doi.org/10.1038/s41598-017-05869-x |
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