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Altered Tracer Distribution and Clearance in the Extracellular Space of the Substantia Nigra in a Rodent Model of Parkinson's Disease

The relationship between extracellular space (ECS) diffusion parameters and brain drug clearance is not well-studied, especially in the context of Parkinson's disease (PD). Therefore, we used a rodent model of PD to explore the distribution and clearance of a magnetic resonance tracer. Forty ma...

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Detalles Bibliográficos
Autores principales: Fang, Yuan, Dong, Yanchao, Zheng, Tao, Du, Dan, Wen, Jiexia, Gao, Dawei, Liu, Lanxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524830/
https://www.ncbi.nlm.nih.gov/pubmed/28790882
http://dx.doi.org/10.3389/fnins.2017.00409