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The Calcineurin-Binding, Activity-Dependent Splice Variant Dynamin1xb Is Highly Enriched in Synapses in Various Regions of the Central Nervous System

In the present study, we generated and characterized a splice site-specific monoclonal antibody that selectively detects the calcineurin-binding dynamin1 splice variant dynamin1xb. Calcineurin is a Ca(2+)-regulated phosphatase that enhances dynamin1 activity and is an important Ca(2+)-sensing mediat...

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Detalles Bibliográficos
Autores principales: Eich, Marie-Lisa, Dembla, Ekta, Wahl, Silke, Dembla, Mayur, Schwarz, Karin, Schmitz, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524891/
https://www.ncbi.nlm.nih.gov/pubmed/28790889
http://dx.doi.org/10.3389/fnmol.2017.00230

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