Cargando…

Connexin hemichannel blockade improves survival of striatal GABA-ergic neurons after global cerebral ischaemia in term-equivalent fetal sheep

Basal ganglia injury at term remains a major cause of disability, such as cerebral palsy. In this study we tested the hypotheses that blockade of astrocytic connexin hemichannels with a mimetic peptide would improve survival of striatal phenotypic neurons after global cerebral ischaemia in term-equi...

Descripción completa

Detalles Bibliográficos
Autores principales: Galinsky, Robert, Davidson, Joanne O., Lear, Christopher A., Bennet, Laura, Green, Colin R., Gunn, Alistair J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524909/
https://www.ncbi.nlm.nih.gov/pubmed/28740229
http://dx.doi.org/10.1038/s41598-017-06683-1